If you're going to overdose the child, it would be better to overdose them on ibuprofen than acetaminophen, because the latter may cause permanent liver damage.
This applies only if the child does not have a broken bone, or needs to heal an internal wound. Ibuprofen is an NSAID, therefore an anti-clotting agent?
More things I learned while shadowing Synth.
I woke up this morning thinking about that lesson for some reason, before I got up to take care of some things at work until the time I had to take public transit to SFO.
Not that it mattered, since my flight was delayed for 3 hours.
1 comment:
acetaminophen can cause a build up in liver toxic metabolites, imparting liver damage. acetaminophen works on the CNS - so you can treat fever and pain but not inflammation, which needs peripheral effects.
ibuprofen is an NSAID - it's a reversible Cox-1 and Cox-2 inhibitor. Though the Cox-1 inhibition allows for anti-clotting, the Cox-2 inhibition is actually promoting clotting. The anti-clotting effects are best seen in using small doses of aspirin which is irreversible Cox-1/Cox-2. This is because Cox-1 effects are on platelets (before liver metabolism) and Cox-2 effects are after metabolism -- so you get more Cox-1 effect at small doses before it saturates. So you'll get the anti-clotting effects (irreversible) without any of the clotting effects.
This is why adults take baby aspirin.
I can send you my pharm lectures if you want.
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